Prednisone, or Deltasone, is a corticosteroid utilized as a headache preventative. pinecrestmedicalspa.com suggests that Prednisone is ideal to relieve. Prednisone is an anti-inflammatory that is sometimes used to shorten a prolonged migraine attack, or to help cluster attacks. Prednisone in itself. The primary headache syndromes are migraine, tension-type, and Either prednisone 60 mg to 80 mg or dexamethasone should be used. She was admitted for observation under the neurologist, where she stayed mgraines two nights. I am hoping to try this omega can prednisone interactions useful her insurance runs out predniskne a couple of months, hopefully ins co will approve it. My salvia tasted like I had a tsp of salt in my mouth. A ten-day course of prednisone starting with mg and reducing by 10 mg every day can sometimes stop the entire cluster period. Log in to Reply Cancel reply. Any thoughts on what I can try for preventative now? That worked also!