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viagra package insert

an oral therapy for erectile dysfunction, is the citrate salt of sildenafil, a selective inhibitor of Protein binding is independent of total drug concentrations. These treatments include pills, medicines that are injected or inserted into the penis. PACKAGE INSERT – DIRECTIONS FOR USE. Viagra mg coated tablets. Sildenafil citrate. Read this package insert carefully before you start taking this. VIAGRA®. 25 mg, 50 mg or mg film-coated tablets. Sildenafil. Package leaflet: Information for the patient. Read all of this leaflet carefully before you start .

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NO then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate cGMP , producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood. Effects of VIAGRA on Vision: At single oral doses of mg and mg, transient dose-related impairment of color discrimination was detected using the Farnsworth-Munsell hue test, with peak effects near the time of peak plasma levels. Drinking alcohol can temporarily impair the ability to get an erection. Although plasma levels of sildenafil at 24 hours post dose are much lower than at peak concentration, it is unknown whether nitrates can be safely co-administered at this time point [ see Contraindications 4. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines. Use with caution in patients with the following underlying conditions which can be particularly sensitive to the actions of vasodilators including VIAGRA — those with left ventricular outflow obstruction e. Especially tell your healthcare provider if you take any of the following: medicines called nitrates see " What is the most important information I should know about VIAGRA? However, since higher plasma levels may increase the incidence of adverse reactions, a starting dose of 25 mg should be considered in older subjects due to the higher systemic exposure [ see Dosage and Administration 2. They may differ from the information contained in this leaflet. You may need to read it again. The primary endpoint was time to limiting angina in the evaluable cohort. A starting oral dose of 25 mg should be considered in those patients [ see Dosage and Administration 2. Make sure your doctor viagr you are taking Viagra. Tell any other doctors, dentists and pharmacists who are treating you that you are taking Viagra. How much to take Your doctor will decide the correct dose for you depending on your condition and response. If Viagra does not help you get an erection or if your erection does not last long enough to complete sexual intercourse, tell your doctor. Decreased blood pressure, syncope, and prolonged erection were reported in some healthy volunteers exposed to high doses of sildenafil — mg. In addition to human corpus cavernosum smooth muscle, PDE5 is also found in other tissues including platelets, vascular and visceral smooth muscle, and skeletal muscle, brain, heart, liver, kidney, lung, pancreas, prostate, bladder, testis, and seminal vesicle. Stronger CYP3A4 inhibitors such as ketoconazole or itraconazole could be expected to have greater effects than seen with saquinavir. Clinical data have shown that co-administration with saquinavir or erythromycin increased plasma levels of viabra by about 3 source [ see Drug Interactions 7. viagra package insert

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Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine. See "Before you take Viagra" for a list of common nitrate medications. Stepwise increase in alpha-blocker dose may be associated with further lowering of blood pressure when taking a PDE5 inhibitor. Sildenafil is only about fold as potent for PDE5 compared to PDE6, an enzyme found in the retina which is involved in the phototransduction pathway of the retina. Clinical data have shown that co-administration with saquinavir or erythromycin increased plasma levels of sildenafil by about 3 fold [ see Drug Interactions 7. This site is provided for educational and informational purposes only, in accordance with our Terms of Use , and is not intended as a substitute for the advice of a medical doctor, nurse, nurse practitioner or other qualified health professional. If you need emergency medical care for a heart problem, it will be important for your healthcare provider to know when you last took VIAGRA. Based on effectiveness and toleration, the dose may be increased to a maximum recommended dose of mg or decreased to 25 mg. Viagra is used to treat erectile dysfunction, more commonly known as impotence, in men.

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